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AEDInitial8-10 mg/kg/day PO divided q12hrmay increase qWeek by maximum increment of 10 mg/kg/day AED-naiveInitial 8-10 mg/kg/day PO divided q12hrmay increase q3Days by 5 mg/kg/day Target maintenanceWeight-based dosing may be as high as 2100 mg/day for60 kg 20-24.99 kg600-900 mg/day 25-34.99 kg900-1200 mg/day 35-44.99 kg900-1500 mg/day 45-49.99 kg1200-1500 mg/day 50-59.99 kg1200-1800 mg/day 60-69.99 kg1200-2100 mg/day 70 kg1500-2100 mg/day.

Like other antiepileptic drugsTRILEPTAL may cause suicidal thoughts or actions in a very small number of peopleabout 1 in 500.

Use during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Table 5 lists adverse reactions in a controlled clinical study of monotherapy in adults not previously treated with other AEDs that occurred in at least 2of adult patients with epilepsy treated with TRILEPTAL or placebo and were numerically more common in the patients treated with TRILEPTAL.

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