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In clinical pharmacologic studiessimultaneous administration of carbidopa and levodopa produced greater urinary excretion of levodopa in proportion to the excretion of dopamine than administration of the two drugs at separate times.
All patients should be observed carefully for the development of depression with concomitant suicidal tendencies.
Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficulty breathingswelling of your facelipstongueor throat.
Levodopa has been detected in human milkCaution should be exercised when SINEMET is administered to a nursing woman.
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