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Some products that may interact with this drug includedrugs removed from your body by certain liver enzymes including vinblastineantiarrhythmics such as propafenone/flecainidetricyclic antidepressants such as desipramine/imipramineother drugs that can cause bleeding/bruising including antiplatelet drugs such as clopidogrelNSAIDs such as ibuprofenblood thinnerssuch as warfarin.

IntermittentSarafem20 mg PO qDay starting 14 days before menstruation and through first full day of mensesrepeat each cycle)

Take this medication by mouth as directed by your doctorusually once daily in the morningIf you are taking this medication twice a dayyour doctor may direct you to take it in the morning and at noon.

Table 6Treatment-Emergent Adverse ReactionsIncidence in Female Patients Ages 18 to 45 Years in Depress ionOCDand Bulimia Placebo-Controlled US Clinical Trials.

Fluoxetine has not been systematically studiedin animals or humansfor its potential for abusetoleranceor physical dependenceWhile the pre-marketing clinical experience with fluoxetine did not reveal any tendency for a withdrawal syndrome or any drug seeking behaviorthese observations were not systematic and it is not possible to predict on the basis of this limited experience the extent to which a CNS active drug will be misuseddivertedand/or abused once marketedConsequentlyphysicians should carefully evaluate patients for history of drug abuse and follow such patients closelyobserving them for signs of misuse or abuse of SARAFEMfor exampledevelopment of toleranceincrementation of dosedrug-seeking behavior

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