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In all of these studiesthe main measure of effectiveness was the change in the number of seizures before and during treatment.
Lower doses are used in patients who have problems with their kidneyssuch as older patients
KEPPRA is indicated as adjunctive therapy in the treatment of primary generalized tonic-clonic seizures in adults and children 6 years of age and older with idiopathic generalized epilepsy.
The CLcr in ml/min/1.73 m 2 may be estimated from serum creatininemg/dldeterminationfor young adolescentschildren and infantsusing the following formulaSchwartz formula
(2A 10.5 mg/kg0.105 ml/kgloading dose is recommended on the first day of treatment with levetiracetam.
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