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Caution in severe hepatic cirrhosisdo not exceed 150 mg every other daymild-moderate hepatic impairmenthead trauma and prior seizure historyCNS tumorconcomitant meds lowering seizure threshold.

Initial150 mg orally once/daymay adjust to 150 mg every 12 hours after 3 days May increase to no more than 200 mg every 12 hours after more than 4 weeks if no clinical improvement observed with 150 mg every 12 hours.

Coadministration of any other medications that contain bupropionbecause seizures are dose dependent.

Screen patients for bipolar disorder and monitor for these symptomsmay precipitate manichypomanic or mixed episodes in patients with bipolar disorder.

Decreased memory3450 mg/daymay be increased risk with concomitant ECT)

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bupropion aplenzin, wellbutrin xl is also used to treat seasonal affective disorder sad, episodes of depression that occur at the same time each year usually in the fall and winter but rarely may occur in the spring or summer months .

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