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Many drugs can interact with methotrexateThis includes prescription and over-the-counter medicinesvitaminsand herbal productsNot all possible interactions are listed hereTell your doctor about all your current medicines and any medicine you start or stop using.

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Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you have low blood cell countsa bone marrow disorderliver diseaseespecially if caused by alcoholismor if you are pregnant or breast-feeding.

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