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Advise the patient to use the medicine only as directedto take a missed dose as soon as possibleunless it is almost time for the next doseand not to double the next dose.

0.1 mg/day PO in combination with high salt diet and adequate fluid intakemay be increased in increments of 0.1 mg/wknot to exceed 1 mg/day.

Prolonged use of corticosteroids may produce posterior subcapsular cataractsglaucoma with possible damage to the optic nervesand may enhance the establishment of secondary ocular infections due to fungi or viruses.

Children who are on immunosuppressant drugs are more susceptible to infections than healthy childrenChicken pox and measlesfor examplecan have a more serious or even fatal course in children on immunosuppressant corticosteroidsIn such childrenor in adults who have not had these diseasesparticular care should be taken to avoid exposureIf exposedtherapy with varicella zoster immune globulinVZIGor pooled intravenous immunoglobulinIVIGas appropriatemay be indicatedIf chicken pox developstreatment with antiviral agents may be considered.

Infants born of mothers who have received substantial doses of fludrocortisone acetate during pregnancy should be carefully observed for signs of hypoadrenalism.

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florinef contains fludrocortisone acetate as the active ingredient.

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