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Researchers think that Cymbalta helps calm down these pain signals by increasing the level of two naturally occurring substances called serotonin and norepinephrineThese substanceswhich are found in the brain and other parts of the nervous systemcan affect mood and are believed to help control and suppress feelings of painCymbalta and other SNRIs block serotonin and norepinephrine from re-entering cellsand therefore increase the levels of these substancesThis process is thought to improve mood and relieve pain in patients with fibromyalgia.

It may take 1 to 4 weeks before your symptoms improveKeep using the medication as directedDo not stop using Cymbalta without first talking to your doctorYou may have unpleasant side effects if you stop taking this medicine suddenly.

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It is not known whether duloxetine will harm an unborn babyHoweverCymbalta may cause problems in a newborn if you take the medicine during the third trimester of pregnancyTell your doctor if you are pregnant or plan to become pregnant while using this medicine.

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