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If you also take certain drugs to lower your cholesterolbile acid-binding resins such as cholestyramine or colestipoltake propranolol at least 1 hour before or at least 4 hours after these medications.

RaceA study conducted in 12 white and 13 African-American male subjects taking immediate-release propranolol showedthat at steady statethe clearance of Rand S-propranolol were about 76and 53higher in African-Americans than in whitesrespectively.

GastrointestinalNauseavomitingepigastric distressabdominal crampingdiarrheamesenteric arterial thrombosisischemic colitis.

Impact of Other Drugs on Propranolol CYP2D6CYP1A2and CYP2C19 InhibitorsCYP2D6 inhibitorse.gbupropionfluoxetineparoxetinequinidineCYP1A2 inhibitorse.gciprofloxacinenoxaminefluvoxamineand CYP2C19 inhibitorse.gfluconazolefluvoxamineticlopidineincrease exposure to propranolol when co-administered with INNOPRAN XLMonitor patients for bradycardia and hypotensionsee Clinical Pharmacology12.7

The plasma levels of propranolol showed dose-proportional increases after single and multiple administration of 80120and 160mg of INNOPRAN XL.

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