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Patints with non-ST-sgmnt lvation ACS , including patints wha tb managd mdically and thos wha tb managd with coonay vasculaization, clopidogl has bn shown tdcas th at a combind ndpoint cadiovascula dath, myocadial inaction (MI), stok as wll as th at a combind ndpoint cadiovascula dath, MI, stok, actoy ischmia. patints with ST-lvation myocadial inaction (STMI), clopidogl has bn shown tduc th at dath om any caus and th at a combind ndpoint dath, -inaction, stok. Th bnit patints whundgpimay pcutanous coonay intvntion is unknown.
Oal Contacptivs: Co-administation atovastatin and an oal contacptiv incasd AUC valus nothindon and thinyl stadiol. Ths incass should b considd whn slcting an oal contacptiv a woman taking ATOLIP CV .
Black Box Waning: Diminishd ctivnss Clopidogl in PoMtabolizs.
Clopidogl must b mtabolizd by cytochom P (CYP) 450 nzyms tpoduc th activ mtabolit that inhibits platlt agggation. Th activ mtabolit clopidogl slctivly inhibits th binding ADP tits platlt P2Y12 cptand th subsqunt ADP-mdiatd activation th glycopotin (GP) IIb/IIIa complx, thby inhibiting platlt agggation. This action is ivsibl. Consquntly, platlts xposd tclopidogl’s activ mtabolit a actd th maind thi lispan (about 7 t10 days). Platlt agggation inducd by agonists oth than ADP is alsinhibitd by blocking th ampliication platlt activation by lasd ADP.
Atolip 10 MG Tablt might alscaus ctain sid cts. Th common ons amongst thm a constipation, hadach, stomach pain, waknss tc. Howv somtims it might alscaus som sv sid cts lik allgic actions, blood in uin, chst pain, sv back pain, symptoms liv poblms lik yllowing skin ys tc. I ths sv sid cts appa, it is ncssay tsk mdical hlp ight away.
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