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Physical causes are the main reasons for erectile dysfunctionThey include heart diseasehigh blood pressurediabetesneurological diseasemedication side effectsand other health conditionsPsychological causes of erectile dysfunction include anxietydepressionstressand problems in relationshipsLifestyle factors that increase the risk for erectile dysfunction include smokingalcohol useand other substance abuseIntroduction.
The man’s central nervous system stimulates the release of a number of chemicalsincluding nitric oxidewhich is essential for producing and maintaining an erectionNitric oxide stimulates the production of cyclic GMPa chemical that relaxes the smooth muscles in the penisThis allows blood to flow into the tiny pool-like cavernous sinusesflooding the penisThis increased blood flow nearly doubles the diameter of the spongy chambersThe veins surrounding the chambers are squeezed almost completely shut by this pressureThe veins are unable to drain blood out of the penis and so the penis becomes rigid and erectAfter ejaculation or climaxcyclic GMP is broken down by an enzyme called phosphodiesterase-5pde5causing the penis to become flaccidunerectagainImportant substances for erectile health.
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