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Concomitant strong cyp3a4 inhibitors eg, itraconazole, ketoconazole, posaconazole, voriconazole, hiv protease inhibitors, boceprevir, telaprevir, erythromycin, clarithromycin, telithromycin, nefazodone , gemfibrozil, cyclosporine, danazol.

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Erythromycin was previously recommended by the American Heart Association for prophylaxis prior to dentaloral and upper respiratory tract procedures in at-riskpenicillin-allergic patientsIt is no longer recommended because of the high incidence of gastrointestinal adverse effects and complicated pharmacokinetics of the various formulationsHoweverpatients who have successfully received erythromycin for prophylaxis in the past may continue with this regimen if desiredCurrentlyclindamycinfirst-generation cephalosporinsin patients who have not had an IgE-mediated anaphylactic reaction to penicillinazithromycin or clarithromycin are drugs of choice for prophylaxis in penicillin-allergic patients undergoing oraldentalrespiratory tract or esophageal procedures.

Rememberkeep this and all other medicines out of the reach of childrennever share your medicines with othersand use erythromycin only for the indication prescribed.

Combining erythromycin with ergotamine or ydroergotamine has been associated with acute ergot toxicityThis combination should be avoided.

A serious allergic reaction is an emergencyContact a doctor straight away if you think you or someone around you is having a serious allergic reaction.

The usual dose of erythromycin is 250mg to 1,000mg taken 4 times a daySometimes it’s taken twice a dayThe dose may be lower for children.

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the presence of 10 stereospecific carbons and several points of distinct substitution has made the total synthesis of erythromycin a a formidable task.

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